Searchable abstracts of presentations at key conferences in endocrinology

ea0044p198 | Obesity and Metabolism | SFEBES2016

Progesterone and estrogen regulation of gene expression related to acylation stimulating protein production and function in ex vivo adipose tissue explant culture

Al Riyami Bashair , Langley-Evans Simon , Salter Andrew , Saleh Jumana

Acylation stimulating protein (ASP) synthesis occurs through the interaction between complement C3, factor B and adipsin in adipose tissue. ASP demonstrates potent lipogenic effects that are modulated by sex hormones in vivo and in vitro. In this study, an ex vivo investigation was carried out to analyse expression of genes related to ASP production and function. Adipose tissue was harvested from ovariectomized rats (n=6), and treated with s...